Ultrastructural EM applications

The ER-C Ultrastructural EM user facility is offering technical and scientific support to our academic and industrial users in EM methodologies. We provide access to life science research approaches complementing our high-resolution Cryo-EM facility at the Ernst Ruska-Centre, Forschungszentrum Jülich.

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Publications

Rollenhagen A, Anstötz M, Zimmermann K, Kasugai Y, Sätzler K, Molnar E, Ferraguti F, Lübke JHR. Layer-specific distribution and expression pattern of AMPA- and NMDA-type glutamate receptors in the barrel field of the adult rat somatosensory cortex: a quantitative electron microscopic analysis. 2022 Cereb Cortex 22:bhac212
Rollenhagen A, Walkenfort B, Yakoubi R, Klauke SA, Schmuhl-Giesen SF, Heinen-Weiler J, Voortmann S, Marshallsay B, Palaz T, Holz U, Hasenberg M, Lübke JHR. Synaptic Organization of the Human Temporal Lobe Neocortex as Revealed by High-Resolution Transmission, Focused Ion Beam Scanning, and Electron Microscopic Tomography. 2020 Int J Mol Sci. 21(15):5558
Yakoubi R, Rollenhagen A, von Lehe M, Miller D, Walkenfort B, Hasenberg M, Sätzler K, Lübke JH. Ultrastructural heterogeneity of layer 4 excitatory synaptic boutons in the adult human temporal lobe neocortex. 2019b Elife. 8:e48373
Rollenhagen A, Ohana O, Sätzler K, Hilgetag CC, Kuhl D, Lübke JHR. Structural Properties of Synaptic Transmission and Temporal Dynamics at Excitatory Layer 5B Synapses in the Adult Rat Somatosensory Cortex. 2018 Front Synaptic Neurosci.10:24
Rollenhagen A, Sätzler K, Rodríguez EP, Jonas P, Frotscher M, Lübke JH. Structural determinants of transmission at large hippocampal mossy fiber synapses. 2007 J Neurosci. 27(39):10434-44
Pipich et al. 2021:  V. Pipich, T. Starc, J. Buitenhuis, R. Kasher, W. Petry, Y. Oren and D. Schwahn, Silica fouling in reverse osmosis systems-Operando small-angle neutron scattering studies, Membranes 11 (2021) 413, 1-35. [10.3390/membranes11060413]
Klein et al. 2016:  A.N. Klein, T. Ziehm, M. Tusche, J. Buitenhuis, D. Bartnik, A. Boeddrich, T. Wiglenda, E. Wanker, S.A. Funke, O. Brener, L. Gremer, J. Kutzsche and D. Willbold, Optimization of the all-D peptide D3 for Ab oligomer elimination, PLoS ONE 11 (2016) e0153035. [10.1371/journal.pone.0153035]
Zhang et al. 2010:  Z. Zhang, J. Buitenhuis, A. Cukkemane, M. Brocker, M. Bott and J. K. G. Dhont, Charge reversal of the rodlike colloidal fd virus through surface chemical modification, Langmuir 26 (2010), 10593. [10.1021/la100740e]