Immunohistochemistry with different detecting systems

Immunohistochemistry (with different detecting systems e.g., DAB or different immunogold particles for multiple labeling) combined with quantitative analyses is a technique to detect the amount and location of different receptor types or proteins on the ultrastructural level.

Connexin43 protein labeled by immunogold particles (silver enhanced nanogold) in astroglial processes near synaptic complexes. Taken from: (Cheung et al. Nat Commun 2022).