Locscale is a density scaling (sharpening) procedure that aims to enhance interpretability of cryo-EM density maps.
LocScale is developed in the Sachse lab at EMBL by Arjen Jakobi and can be accessed via GitLab.
Model-based local density sharpening of cryo-EM maps
eLife 2017;6:e27131, doi: 10.7554/eLife.27131