Local density scaling/sharpening of cryo-EM maps

Locscale is a density scaling (sharpening) procedure that aims to enhance interpretability of cryo-EM density maps.


LocScale is developed in the Sachse lab at EMBL by Arjen Jakobi and can be accessed via GitLab.

Arjen J Jakobi, Matthias WilmannsCarsten Sachse,

Model-based local density sharpening of cryo-EM maps

eLife 2017;6:e27131, doi: 10.7554/eLife.27131