{"id":4031,"date":"2021-05-14T22:18:38","date_gmt":"2021-05-14T22:18:38","guid":{"rendered":"https:\/\/er-c.org\/?page_id=4031"},"modified":"2025-01-15T11:05:24","modified_gmt":"2025-01-15T11:05:24","slug":"fdr-fsc","status":"publish","type":"page","link":"https:\/\/er-c.org\/index.php\/software\/cryo-em\/fdr-fsc\/","title":{"rendered":"FDR-FSC"},"content":{"rendered":"<div class=\"wp-block-image is-style-default ticss-f091b683\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"626\" height=\"240\" src=\"https:\/\/er-c.org\/wp-content\/uploads\/2021\/03\/Software.jpg\" alt=\"\" class=\"wp-image-1513\" style=\"width:1200px;height:190px\" srcset=\"https:\/\/er-c.org\/wp-content\/uploads\/2021\/03\/Software.jpg 626w, https:\/\/er-c.org\/wp-content\/uploads\/2021\/03\/Software-300x115.jpg 300w\" sizes=\"auto, (max-width: 626px) 100vw, 626px\" \/><\/figure>\n<\/div>\n\n<div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-headline so-widget-sow-headline-default-feea9c97c678\"\n\t\t\t\n\t\t><div class=\"sow-headline-container \">\n\t\t\t\t\t\t\t<h1 class=\"sow-headline\">\n\t\t\t\t\t\tFDR-FSC\t\t\t\t\t\t<\/h1>\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"decoration\">\n\t\t\t\t\t\t<div class=\"decoration-inside\"><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"sow-sub-headline\">\n\t\t\t\t\t\tStatistical FSC resolution estimation of cryo-EM maps\t\t\t\t\t\t<\/h3>\n\t\t\t\t\t\t<\/div>\n<\/div>\n\n\n<div id=\"wp-block-themeisle-blocks-advanced-columns-27948cc6\" class=\"wp-block-themeisle-blocks-advanced-columns has-1-columns has-desktop-equal-layout has-tablet-equal-layout has-mobile-equal-layout has-vertical-unset has-default-gap\"><div class=\"wp-block-themeisle-blocks-advanced-columns-overlay\"><\/div><div class=\"innerblocks-wrap\">\n<div id=\"wp-block-themeisle-blocks-advanced-column-cf76d8a1\" class=\"wp-block-themeisle-blocks-advanced-column\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:10%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:80%\">\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p style=\"text-align: justify;\">FDR-FSC is a robust cryo-EM map resolution estimation tool that thresholds the Fourier Shell correlation curve by statistical permutation testing including false discovery rate control. The procedure accepts untreated half-maps and does not require any solvent-flattening masking. &nbsp;<\/p>\n<p style=\"text-align: justify;\">It was developed by the ER-C-3 institute and can be found here:<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill\"><a class=\"wp-block-button__link has-white-color has-text-color has-background wp-element-button\" href=\"https:\/\/erc-3-cloud.fz-juelich.de\/FSC_Server\/\" style=\"background-color:#023d6b\" target=\"_blank\" rel=\"noreferrer noopener\">Access<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div id=\"citationDataDisplay\" class=\"transparent\">\n<div id=\"citationText\" tabindex=\"0\">\n<p class=\"mb-0 ml-4\" style=\"text-align: left;\">M. Beckers and C. Sachse, &#8216;Permutation testing of Fourier shell correlation for resolution estimation of cryo-EM maps&#8217; <i>Journal of Structural Biology, 212 (2020), 107579<\/i><\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill\"><a class=\"wp-block-button__link has-white-color has-text-color has-background wp-element-button\" href=\"https:\/\/doi.org\/10.1016\/j.jsb.2020.107579\" style=\"background-color:#023d6b\" target=\"_blank\" rel=\"noreferrer noopener\">View Article<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:10%\"><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":3887,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-4031","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/er-c.org\/index.php\/wp-json\/wp\/v2\/pages\/4031","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/er-c.org\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/er-c.org\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/er-c.org\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/er-c.org\/index.php\/wp-json\/wp\/v2\/comments?post=4031"}],"version-history":[{"count":9,"href":"https:\/\/er-c.org\/index.php\/wp-json\/wp\/v2\/pages\/4031\/revisions"}],"predecessor-version":[{"id":9682,"href":"https:\/\/er-c.org\/index.php\/wp-json\/wp\/v2\/pages\/4031\/revisions\/9682"}],"up":[{"embeddable":true,"href":"https:\/\/er-c.org\/index.php\/wp-json\/wp\/v2\/pages\/3887"}],"wp:attachment":[{"href":"https:\/\/er-c.org\/index.php\/wp-json\/wp\/v2\/media?parent=4031"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}